Triptolide, 2-hydroxy-, (2-beta)-
Tripdiolide
CAS: 38647-10-8
Molecular Formula: C20H24O7
Triptolide, 2-hydroxy-, (2-beta)- - Names and Identifiers
| Name | Tripdiolide |
| Synonyms | nsc163063 Tripdiolid NSC 163063 TRIPDIOLIDE Tripdiolide Triptodiolide TRIPTODIOLIDE (2-beta)-triptolid 7as,7bs,8as,8bs,10s)-6ar 2BETA-HYDROXY-TRIPTOLIDE (2beta)-2-Hydroxytriptolide Triptolide, 2-hydroxy-, (2-beta)- Triptolide, 2-hydroxy-, (2beta)- (9CI) 8b,9,10-decahydro-6,10-dihydroxy-8b-methyl-6a-(1-methylethyl)-,(3bs,4as,5as,6 |
| CAS | 38647-10-8 |
| InChI | InChI=1/C20H24O7/c1-7(2)18-13(26-18)14-20(27-14)17(3)5-10(21)12-8(6-24-15(12)22)9(17)4-11-19(20,25-11)16(18)23/h7,9-11,13-14,16,21,23H,4-6H2,1-3H3/t9-,10-,11-,13-,14-,16+,17-,18-,19+,20+/m0/s1 |
Triptolide, 2-hydroxy-, (2-beta)- - Physico-chemical Properties
| Molecular Formula | C20H24O7 |
| Molar Mass | 376.41 |
| Density | 1.56±0.1 g/cm3(Predicted) |
| Melting Point | 226-228 °C |
| Boling Point | 656.4±55.0 °C(Predicted) |
| Flash Point | 240.5°C |
| Vapor Presure | 5.11E-20mmHg at 25°C |
| pKa | 13.50±0.70(Predicted) |
| Refractive Index | 1.668 |
Triptolide, 2-hydroxy-, (2-beta)- - Reference Information
| overview | triptolide (Tripdiolide), also known as triptolide diol, is a diterpene lactone component in tripterygium wilfordii. Studies have shown that triptolide B has anti-inflammatory, immunosuppressive, anti-tumor and treatment of diabetic nephropathy, and has good medicinal development prospects. |
| use | tripterygium is the main active ingredient of tripterygium wilfordii, and is also the main effective ingredient of tripterygium wilfordii polyglycoside tablets and tripterygium wilfordii total terpene tablets. Clinically, it is often used to treat refractory hyperimmune diseases such as rheumatoid arthritis, chronic nephritis, and lupus erythematosus. |
Last Update：2024-04-09 21:01:54
